The Guigang Cultural and Art Center in Guangxi Province is a large-scale public building consisting of three main parts, the Grand Theatre, the Mass Art Museum and the Science and Technology Museum, and a public area, with a total building area of 113, 000 square meters. The project faces many difficulties, including wide construction area, tight construction period, large-scaled electro-mechanical engineering, high requirement for indoor decoration effect, difficult construction of steel facade flow surface, and high requirement for construction organization of roof steel membrane structure. Through the application of BIM technology in the construction phase, the project team has achieved more than ten targeted applications, including BIM modeling, electro-mechanical pipeline collision and optimization, refined decoration deepening and application, BIM engineering quantity calculation comparison, BIM5D site management, BIM-based green construction management, BIM application in guiding concrete pouring of large-scaled raft slab concrete, overlap of complex joints of steel structure, output and drawing based on Tekla Structures, AR display of detailed structure of steel structure model, construction of steel structure flowing skin, and etc. The application of BIM technology guarantees the successful implementation of the project, and provides scientific and technological support for the informatization application of the project and the improvement of quality and efficiency.