Shield construction technology is widely used in the construction of the subway engineering, but at present, domestic and foreign studies on shield tunneling parameters are comparatively less, among which most is about EPB shield. Research on multiple linear regression analysis of slurry shield construction parameters has become almost an empty field. Therefore, it is necessary to study multiple linear regression analysis slurry shield construction parameters to ensure the safety of the construction process and to reduce project cost as well as the adverse impact of subway construction. This article takes the example of the 757 to 1460 of the left line of shield construction data of Wuhan metro line 4, uses SPSS statistical software for statistical data analysis and establishes the multiple linear regression models of the total thrust and torque. The multiple linear regression models can be used to predict the total thrust and torque of the construction. With the right line shield construction field data for engineering verification, it is found that the predicted results are in good agreement with the actual results.