Building Information Modeling (BIM) technology is more and more popular today, more and more projects howe used BIM technology. The design and construction process of the National Oceanographic Museum were guided by the BIM modeling which provided by design institute. As the construction of the project, our team adopted new organizational structure and management mode, guided the construction by the BIM model, applied all kinds of information and functions of BIM model deeply in the process of construction, integrated all the construction professionals, designers, owners, contractors. In construction process, we effectively avoided many conventional problems, also saved the cost and time for the project.