This paper applies the finite element software, MSC.Marc, to study the seismic behavior of precast prestressedfabricated concrete frame connections subjected to low cyclic and reciprocal loading, and the finite element analysis results are compared with theexperimental results.The comparison shows that the numerical simulation results of MSC.Marc, e.g. concrete cracking, specimen deformation, steel strand stress, hysteresis curve and skeleton curve, are in good agreement with the experimental results.It is also proven feasible and reliable to simulate the mechanical characteristics of the connections by using this method.