This paper has explored the application of the BIM Technologies in masonry construction by using a case of Tai Kang Tong Ji (Wuhan) hospital project, which explained how to develop the hole reservation in masonry construction, and also explained how to extract the masonry quantity and to guide its construction by using BIM technologies. As a result, it can reduce the secondary transport of masonry materials and improve the efficiencies of construction, which has provided references for other masonry construction projects.