Design management is difficult but important in project management. It increases the complexities and difficulties during the complex hospital construction project. How to achieve the coordination of design management is a very important topic. This paper has studied the collaborative design management of hospital construction project under the whole process execution mode. Through the analysis of management relationship, decomposition of WBS work content, selection of information collaboration platform, build of system architecture, allocation of responsibilities, and establishment of operation mechanism, a collaborative system of hospital construction project design management based on the whole process consultation is established, aiming to provide reference for the similar type of projects.