The steel hyperbolic roof of Hangzhouxi Railway Station is of large volume. The conventional monitoring methods cannot meet the requirements in terms of speed and comprehensiveness. In order to realize high-precision, high-efficiency, and whole process deformation monitoring of Hangzhouxi Railway Station, 3D laser scanning is used to obtain the whole-process point cloud data. The processed point cloud data is registered with the BIM model to analyze the deviation of single component, construction process and morphological structure, so as to realize the whole-process deformation monitoring. The comparison with the measured data of the total station shows that the 3D scanning deformation monitoring is basically consistent with the data value and standard deviation measured by the total station, the data fluctuation is small, and the monitoring results are stable. It is suitable for the whole-process deformation monitoring of large space steel structure projects.