The structure of Huangshi Intermediate People's Court judgment House belongs to the plane and other irregular high-level structure.There are many problems which lead this building to become a High-rise building.These problems include irregularly reverse among program phase building functional layout, local floor discontinuities, and more wear layer column.This paper describes the optimization of Huangshi Intermediate People's Court Building through the structure optimization, the re-classified structure calculation unit, computing and designing by PKPM, SATWE10 version (September 1, 2011).The structural analysis results show that it can effectively solve the problems of structural regularity overrun through reasonable structure layout, structural selection, and structural computing design, thus realize structural design regularization under seismic action.