One of the research emphases of application and investigation of high strength steel are laid on stability of axial compressed member. After analyzing stability of high strength steel and limitations of design method for stability of high strength steel analyzed, combined with the function of stability analysis of large finite element analysis software ANSYS and model test, stability for axial compressed members of high strength steel are researched, and formulae which parameter includes yield strength of material and slenderness ratio of member is put forward for calculation stability coefficient of axial compressed member of high strength steel. Some important conclusions are arrived at. The research is significant for application and investigation of high strength steel in future.