This paper studies the application of BIM technology in the whole process of nuclear island civil construction of nuclear power station, through the implementation of BIM technology of this project, it will meet the needs of national large-scale nuclear power construction from BIM technology, management and talents, and provide resource reserves in all aspects, so as to provide reference for the BIM application of subsequent nuclear power station construction. In this paper, through the development of BIM reinforcement modeling plug-in, it can quickly establish irregular reinforcement model, and can combine with the site for reinforcement cutting, and export material list; the logic of nuclear island civil engineering construction is complex. BIM technology is used to analyze the interference of complex nodes in the cross dense parts of items. Through the construction logic analysis, the modification and optimization of nodes that cannot be implemented are proposed; steel structure construction requires high precision standard, combined with BIM deepening drawing, import equipment, improve processing standard, reduce error.