Abstract: Guangzhou Baiyun International Airport expansion project is a very large public transport hub construction, with single building area of 680 thousand square meters, involving over 20 specialties. All kinds of specialized equipment are complex, which raises a highly difficult challenge to the implementation of BIM technology. This project adopted various techniques to overcome the difficulties. BIM, used as project management and technical means, is involved in each link of design and construction management, including the collaborative design, comprehensive optimization, pipeline design, deepening the construction organization, schedule management, cost control, quality control, etc. to ensure the successful implementation of the project, which has improved the quality of the engineering construction and integrated project management level, and achieved optimization of technical and economic indicators during the entire project life cycle.