Abstract: Construction site layout is an important part of construction organization and management, which is also the premise and foundation of the project construction.Traditional construction site layout is always based on experience, which causes a lot of unreasonable conditions.This paper applies the systematic layout planning (SLP)method in the layout of the construction site, which based on the research of the correlation of functional zoning in site layout, proposes a feasible plan of site arrangement.Then, various schemes are evaluated through the weighted factor method, and the best one is selected.Result shows that the SLP method is an effective way to solve the optimization problem of the construction site layout, which is able to reduce the cost, as well as lessen the secondary handling of the equipment.The works of this paper can provide reference for the relevant engineering application.