Abstract: The 5th Xiang-Ya hospital of Central South University is one of the first PPP demonstration projects in Hunan Province, and is co-designed by the Payette Company in America and Hunan Architectural Design Institute in China. This paper introduces the process of BIM forward design from scheme design, design development to detailed design. The super-massive 3D model of the hospital building with complex spatial structure is managed using combined local workstation and cloud server platform, and the lightweight model is applied for communication and project controlling, which fully embodies the advantages of BIM's forward design. Special professional medical process design is carried out for the characteristics of hospital buildings, and thein depth implementation of BIM forward design is promoted with the application of technologies including green building analysis, secondary development and programming processing, UAV tilt photography, and etc. The studies in this paper lay a good foundation for the application and expansion of BIM technology in modern medical architecture.