Abstract: The function of pipeline synthesis and deepening design of BIM technology in electromechanical systems is one of the most representative applications of all BIM technologies. This article uses Sun Yat-sen Cardiovascular Hospital as an example to study the application direction of BIM technology in the pipeline synthesis design of hospital building. It includes the coordinated design of the direction, elevation, and hierarchical relationship of important parts such as the layout of the lane bridge, the track logistics trolley, and the air duct of the exhaust fan room; the technical combination of the installation space, the form of the pipe and the height of the ceiling and other important points that are easy to be ignored. The practice has shown that the main points of application of BIM technology in pipeline synthesis design mainly include pipeline collision, headroom analysis and information management, which can significantly improve the overall benefit of hospital buildings.