Abstract: On the basis of combing the interweaving effects of the development of science and technology and the needs of engineering practice, this paper analyzes the historical evolution of the application of engineering cost in construction management, and the influence of the emergence of new artificial intelligence calculation methods on the system thinking characteristics, process organization mode characteristics, information and intelligence characteristics of engineering cost calculation, and discusses the engineering cost information of artificial intelligence project cost construction of management platform. Finally, the artificial intelligence neural network method and genetic algorithm are used to analyze the rapid estimation model of construction cost, which provides a certain reference for the development of engineering cost in artificial intelligence.