New national codes including Code for seismic design of buildings, Code for design of concrete structures and Technical specification for concrete structures of tall building have been published in 2010. A lot of items have been revised base on latest achievements of scientific research and earthquake damage research. How these changes affect structure index and the area of steel reinforcement become the main concern to structural designers. In this paper, a frame structure is analyzed and designed by the new SATWE program and the old one, analyzed and designed results such as overall indexes and the area of steel reinforcement are listed and compared and the following conclusions can be drawn: the beam moment of inertia magnify method, calculation of torsional displacement ratio, considering stairs are the main factors contributing to the overall index difference; the use of high strength steel reinforcement, seismic design grade of structural members, modification of column internal force, calculation of shear capability and checking of serviceability limit states are the main factors contributing to the area of steel reinforcement. The conclusions can be a reference for designers.