Traditional two-dimensional CAD design is still the main trend in the current domestic construction field, and the reinforced drawings mainly rely on flat overall representation in structure industry.As the complexity of engineering projects and the requirement of efficiency and quality continuously rise, the disadvantages of flat overall representation method are gradually revealed, including that it is not intuitive, incomplete of location information, difficult to avoid collision or directly guide construction.This article discusses the automatic generating from flat overall representation to reinforced three-dimensional model, the engineering practice of reinforced three-dimensional model and the relevant improvement of design efficiency and quality.The Cancer (proton) Center, Shanghai Jiao Tong University Affiliated Ruijin Hospital case is used to expound the process of automatic generating and the application of three-dimensional model, including reinforced collision calibration between bar and bar, bar and embedded pan, and in complex nodes, engineering budgeting based on reinforced three-dimensional model, and reinforced compliance check.