This article describes the comprehensive application of BIM technology in the mechanical and electrical installation of the Beijing Headquarters Base Project of China Construction Third Engineering Bureau, covers basic and innovative applications of BIM, and detailed introductes the theoretical application of BIM technology to actual guidance on site construction. And according to the characteristics of the project demand, this article discovers the innovative application points of BIM suitable for current projects, so that BIM technology can truly realize saving materials, reducing cost, increasing efficiency, getting good quality performance of engineering system and convenient operation of the property system. Use BIM technology to carry out auxiliary forward design, optimize the design schemes of water supply and drainage, HVAC and electrical, to ensure the realization and coordinated operation of the MEP system. In the process of BIM implementation of this project, a variety of softwares including Revit, Navisworks, MagiCAD, Xiezhu platform, and Solidworks were used as needed to achieve modeling, deepening, collaboration, calculation, drawing and confession. Different aspects of the needs, all-round services to guide the on-site construction. And through the discovery of innovative applications, the construction speed and quality are improved.