Taking Daheihe Bridge in Hohhot City as the background project, this paper has preliminarily explored the application path of relevant standards of highway engineering information model in the design process of cable-stayed bridges, and has given specific implementation methods from the definition of information model of cable-stayed bridges, design process, modeling requirements, output of construction drawings and selection of modeling and analysis software. The practice of this project shows that the design of cable-stayed bridge based on highway engineering information model can improve the efficiencies of actual work, which has certain practical significance and application prospects.