Driven by the new generation of information technology, systems such as integrated design, standardized manufacture, building information modelling (BIM), internet of things (IoT) and intelligent manufacture techniques are promoting the industrialization of new buildings. This paper takes the third generation command center of Shenzhen municipal public security bureau as an example, explores the whole process BIM application of EPC project under the contract+whole process consulting mode, and strives to break the problem of two sets of models of design and construction stages and find the method to solve the problem between the production process and the organization of construction project by using information technologies which will make the informatization methods create efficiency. Using BIM forward design can improve the quality of models and drawings and realize 0 design changes in design stage. Through recruitment and procurement in the early stage can realize the integration of design and construction, reduce the construction period. And building the intelligent site system can prevent safety accidents and reduce the construction risk. Finally, the paper concludes that the combination of BIM forward design and professional subcontracting under the EPC mode is an effectivee method to realize the integration of design and construction, which will provide the valuable experience for the industrialization of new buildings.