The concept of "Smart City" has been particularly reflected by successfully implemented "Intelligence Construction Site" in Nansha Pearl Bay Youth Palace project. Through combination of technologies (e.g. BIM, IoT, VR, AI, and etc.), an integrated, intelligent and sustainable "Nansha Construction Management Center Intelligence Construction Site" system has been established. This paper has introduced the specific application of the system during the construction stage of Nansha Youth Palace project in the perspective of personnel management, quality management, safety management and environmental protection. This system is aiming to improve management efficiency and to break the "information isolated island", capturing lessens and experiences for the development and the future implementation of intelligence construction site.