To solve the problems that project quality and safety management cannot be intuitively expressed, prevented in advance, and rectified in a timely manner, this paper introduces BIM technology into project safety and quality management, and verifies the feasibility of collaborative management of project safety and quality based on BIM 5D. It is concluded that utilizing BIM technology of "pre prevention" (establishing Revit models, detailing design, construction simulation, and visual construction drawing explanations), project quality potential defects and safety hazards can be exposed in advance, consequently reducing unnecessary troubles caused by rework, ensuring the orderly entry into construction site and reasonable stacking of materials, and providing a foundation for safe and civilized construction; utilizing BIM 5D+smart construction site decision-making system of "in-process control", quality potential defects and safety hazards are collected and analyzed, and the analysis results are presented in charts to provide early warning for key quality potential defects and safety hazards, therefore identifying and rectifying them timely. The Practical application has shown that proposed method can ensure project safety, improve engineering quality, providing a reference for construction enterprises to apply BIM 5D.