The continuous development of the BIM technology has earned itself more attention and importance than ever in the industrial engineering, especially in the construction engineering of large-scaled micro electronic devices plant for the excellent application effects. In this paper, the practical engineering of Shanghai Zhongxin electronic device plant is studied to achieve the maximum benefits of BIM application. In the early stage of project, BIM is applied for deepening drawings and optimizing construction scheme, and during the project implementation stage, BIM is applied for 3D space management, design optimization, construction visualization, and technical disclosure. BIM is also applied in pre-construction stage to implement collision detection and optimization to avoid reconstruction, material scrapping, construction delay and other problems in construction stage. BIM application also contributes to solving the time consuming problem and difficulties in taking off loadings in traditional steel structure installation. The advantages of the SPMT module transportation vehicle is adopted to develop a new technology of rolling installation of large-span steel truss structure based on the SPMT module vehicle. The loading capacity of waffle board and stability of truss during rolling installation have been both double checked through calculation, ensuring the safety and reliability of the construction of rolling installation, which provides technical supports of the following similar construction of large-span steel roof projects.