In that the metro station is always located deep underground with complex and special structure, once a fire breaks out, heavy casualties and property losses are often caused. How to effectively prevent and reduce the casualties in the case of fire, especially to prevent the occurrence of major accidents such as group death, has already become a hot spot and focus of the research in the field of fire control safety all around the world. In order to take timely and effective measures in station fire accidents, and to reduce the range of the impact and loss of the fire accident to the lowest, this paper analyzes the characteristics of the fire in large metro stations, introduces the fire warning systems and the relative warning mechanisms by different classifications. Furthermore, different evacuation modes are analyzed and discussed for different fire occurrence locations in the metro station. This study is of great significance to research the fire safety of large metro stations, and provides references for the design and management of subway stations.