The paper conducts a case study of joint venture general contractor project management information system for international financial center in Guangzhou(Guangzhou West Tower).The author systematically analysis the management characters of super-large engineering, and a project management information system absorbing the latest information technology is developed and successfully used in Guangzhou West Tower project, so management process visualization, computer supported cooperative work, fine management, information sharing and decision supporting are realized.The study provides a domestic leading case, which is an important reference and guide for joint venture general contractor project management information system of super-large engineering.